Endocrine Abstracts

Changes in serum lipid and lipoprotein concentrations occur frequently in disorders of thyroid function. LDL-C oxidation susceptibility is higher in these patients than in normal population. This study aims at assessing lipids, lipoproteins, lipid oxidations and serum paraoxonase activity in patients with subclinical hyperthyroidism. Forty patients were compared with an age and sex matched control group. A fasting blood sample was obtained and serum total cholesterol, triglyce...

Patients with thyroid dysfunction are more susceptible to oxidative stress, and may show enhanced LDL-C oxidation. The purpose of this study was to evaluate serum paraoxonase activity and antioxidants in patients with endogenous subclinical hyperthyroidism.Forty-one subclinical hyperthyroid patients, 30 women and 11 men, aged 47±13 years, and 40 age and sex matched healthy controls were studied. Serum paraoxonase activity, lipid, lipoprotein, oxidiz...